Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330161 | 0.91 | ESR1 (0.48) | PRKCQCSNK1A1CSNK1DESR1MEN1 | |
| SCHEMBL29330255 | 0.90 | ESR1 (0.42) | PRKCQESR1TTBK1TTBK2SYK | |
| SCHEMBL29330425 | 0.90 | ESR1 (0.42) | PRKCQCSNK1A1CSNK1DESR1MEN1 | |
| SCHEMBL29330163 | 0.90 | ESR1 (0.42) | PRKCQESR1SMN1; SMN2TTBK1TTBK2 | |
| SCHEMBL29328747 | 0.89 | EGFR (0.42) | PRKCQCSNK1A1CSNK1DESR1TTBK1 | |
| SCHEMBL29329725 | 0.89 | PRKCQ (0.40) | PRKCQCSNK1A1CSNK1DESR1PRKCD | |
| SCHEMBL29330251 | 0.88 | SYK (0.41) | PRKCQESR1MEN1POLBKMT2A | |
| SCHEMBL29329642 | 0.87 | ABL1 (0.46) | PRKCQESR1TTBK1TTBK2SYK | |
| SCHEMBL29330248 | 0.87 | ESR1 (0.46) | PRKCQESR1TTBK1TTBK2SYK | |
| SCHEMBL29330032 | 0.87 | SYK (0.42) | PRKCQESR1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |