Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330567 | 0.90 | PRKCQ (0.45) | ESR1PRKCQSYKTTBK1TTBK2 | |
| SCHEMBL29330161 | 0.90 | ESR1 (0.48) | ESR1CYP19A1PRKCQSYKTTBK1 | |
| SCHEMBL29330163 | 0.89 | ESR1 (0.42) | ESR1PRKCQSYKTTBK1TTBK2 | |
| SCHEMBL29330255 | 0.89 | ESR1 (0.42) | ESR1PRKCQSYKTTBK1TTBK2 | |
| SCHEMBL29329865 | 0.89 | PRKCQ (0.43) | ESR1CYP19A1PRKCQSYKKCNH2 | |
| SCHEMBL29330256 | 0.89 | PRKCQ (0.41) | ESR1CYP19A1PRKCQSYKMEN1 | |
| SCHEMBL29330251 | 0.87 | SYK (0.41) | ESR1PRKCQSYKMEN1KMT2A | |
| SCHEMBL29329642 | 0.86 | ABL1 (0.46) | ESR1PRKCQSYKTTBK1TTBK2 | |
| SCHEMBL29330341 | 0.86 | PRKCQ (0.39) | ESR1PRKCQSYKMEN1KMT2A | |
| SCHEMBL29330248 | 0.86 | ESR1 (0.46) | ESR1PRKCQSYKTTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |