Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331746 | 0.83 | DAO (0.38) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29332375 | 0.83 | DAO (0.38) | CYP11B1CYP11B2PPARDMAOB | |
| SCHEMBL30938612 | 0.83 | DAO (0.38) | CYP11B1CYP11B2PPARDMAOB | |
| SCHEMBL29331748 | 0.79 | KCNH2 (0.41) | MAPTKCNH2LMNAKMT2A | |
| SCHEMBL29331747 | 0.78 | PPARG (0.40) | PPARAPPARGKCNH2TMEM97MEN1 | |
| SCHEMBL29331745 | 0.77 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331955 | 0.76 | GRM2 (0.36) | CYP19A1LMNA | |
| SCHEMBL29331744 | 0.74 | PTGDR2 (0.38) | CYP19A1 | |
| SCHEMBL29332326 | 0.74 | TAAR1 (0.42) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331944 | 0.72 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |