Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938611 | 0.78 | PPARA (0.39) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331653 | 0.78 | PPARA (0.39) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331660 | 0.77 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29333144 | 0.75 | PTGES (0.44) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331750 | 0.69 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL17654577 | 0.69 | MRGPRX4 (0.49) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL29331710 | 0.68 | MAOB (0.49) | MRGPRX4CNR1 | |
| SCHEMBL29331743 | 0.67 | HTR2A (0.37) | PPARAPPARDPPARGMRGPRX4CTSS | |
| SCHEMBL29331946 | 0.67 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1PPARAPPARD | |
| SCHEMBL22894152 | 0.66 | PPARA (0.54) | PPARAPPARDPTGESALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |