Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331955 | 0.83 | GRM2 (0.36) | PTGDR2CYP19A1PDE2AHRH4CNR1 | |
| SCHEMBL29331747 | 0.82 | PPARG (0.40) | PTGDR2CNR1 | |
| SCHEMBL29331748 | 0.80 | KCNH2 (0.41) | SLC6A4HTR2A | |
| SCHEMBL29331660 | 0.74 | CYP11B1 (0.45) | CYP19A1 | |
| SCHEMBL29331746 | 0.69 | DAO (0.38) | CYP19A1SLC6A4HTR2A | |
| SCHEMBL12784515 | 0.66 | PDE2A (0.47) | PDE2A | |
| SCHEMBL4073435 | 0.66 | DOT1L (0.39) | — | |
| SCHEMBL22686159 | 0.66 | KCNH2 (0.42) | SLC6A4HTR2A | |
| SCHEMBL84043 | 0.65 | PDE2A (0.53) | PDE2A | |
| SCHEMBL5030111 | 0.65 | PIK3CD (0.34) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |