Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704087 | 0.88 | ALDH1A1 (0.50) | AVPR2ALDH1A1TSHRUSP2LMNA | |
| SCHEMBL2705045 | 0.86 | AVPR2 (0.47) | AVPR2POLBALDH1A1TSHRUSP2 | |
| SCHEMBL2933189 | 0.84 | AVPR2 (0.52) | AVPR2POLBNR3C2ALDH1A1TSHR | |
| SCHEMBL1346004 | 0.80 | AVPR2 (0.69) | AVPR2 | |
| Hydrochloric Acid SCHEMBL4195564 | 0.79 | AVPR2 (0.68) | AVPR2 | |
| SCHEMBL5230382 | 0.78 | AVPR2 (0.57) | AVPR2NOTUM | |
| Hydrochloric Acid SCHEMBL5235888 | 0.78 | AVPR2 (0.47) | AVPR2 | |
| SCHEMBL7353012 | 0.78 | POLB (0.64) | AVPR2POLBNR3C2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL5270039 | 0.77 | AVPR2 (0.56) | AVPR2 | |
| SCHEMBL2938323 | 0.77 | AVPR2 (0.46) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |