Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977098 | 0.77 | KMT2A (0.51) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL7334106 | 0.77 | LMNA (0.68) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL30074433 | 0.76 | NPC1 (0.61) | KMT2APOLBALDH1A1MEN1NPC1 | |
| SCHEMBL16136596 | 0.73 | EGFR (0.62) | GAANPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL28228415 | 0.72 | ALDH1A1 (0.48) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL3869333 | 0.71 | KMT2A (0.68) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL5426350 | 0.71 | NPC1 (0.82) | KMT2AALDH1A1GAAMEN1NPC1 | |
| SCHEMBL28524761 | 0.71 | NPC1 (0.54) | KMT2APOLBALDH1A1NPC1RAB9A | |
| SCHEMBL233829 | 0.70 | ALDH1A1 (0.69) | KMT2AALDH1A1GAAMEN1NPC1 | |
| SCHEMBL29331886 | 0.70 | NPSR1 (0.49) | KMT2APOLBGAAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150252-A1 | PYRAZOLIDINE-3, 5-DIONE BASED COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2024-07-18 | — | — | WO | disclosed |