SCHEMBL29334667

SCHEMBL29334667

N#Cc1ccc(S(=O)(=O)c2cc(-n3c4ccccc4c4c5c6ccccc6n(-c6ccccc6)c5ccc43)cc(-n3c4ccccc4c4c5c6ccccc6n(-c6ccccc6)c5ccc43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR6 P50406 5/20 0.39
CTSG P08311 1/20 0.38
CMA1 P23946 1/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
USP14 P54578 2/20 0.36
AKT1 P31749 1/20 0.35
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
MAPT P10636 1/20 0.34
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
THRB P10828 1/20 0.33
G6PD P11413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29335106 0.99 HTR6 (0.38) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29334579 0.93 KDM4E (0.42) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29335041 0.92 KDM4E (0.41) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29338484 0.92 KDM4E (0.37) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29335461 0.91 KDM4E (0.40) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29334673 0.89 KDM4E (0.40) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29334832 0.89 KDM4E (0.43) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29335177 0.89 KDM4E (0.40) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29335039 0.88 KDM4E (0.39) KDM4EATML3MBTL1HTR6CTSG
SCHEMBL29334594 0.85 CTSG (0.42) KDM4EATML3MBTL1HTR6CTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151172-A1 CYANODIPHENYL SULFONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, AN EMISSIVE LAYER CONTAINING THEM, AN ELECTROLUMINESCENT DEVICE, AND THEIR USE Noctiluca S.A. (PL) 2024-07-18 WO disclosed