Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29334954 | 0.89 | EPHX2 (0.65) | EPHX2NR1H4MEN1PKMKMT2A | |
| SCHEMBL12619647 | 0.76 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL5616127 | 0.76 | MMP13 (0.58) | EPHX2NR1H4MEN1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL27624751 | 0.76 | EPHX2 (0.71) | EPHX2NR1H4MEN1PKMKMT2A | |
| SCHEMBL20287493 | 0.76 | EPHX2 (0.73) | EPHX2NR1H4PPARG | |
| SCHEMBL29598294 | 0.76 | EPHX2 (0.73) | EPHX2NR1H4PPARG | |
| SCHEMBL4891141 | 0.75 | TRPV1 (0.76) | EPHX2NR1H4 | |
| SCHEMBL29334957 | 0.75 | EPHX2 (0.65) | EPHX2NR1H4MEN1KMT2APPARG | |
| SCHEMBL3932771 | 0.74 | KIF11 (0.50) | MEN1KMT2AALDH1A1GRIN1GRIN2B | |
| SCHEMBL29334958 | 0.74 | EPHX2 (0.70) | EPHX2NR1H4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064923-A9 | COVALENT, CHEMOGENETIC ACTIVATORS FOR K2P POTASSIUM CHANNELS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-18 | — | — | WO | disclosed |