⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649189 | 0.76 | — | — | |
| SCHEMBL21350250 | 0.69 | — | — | |
| SCHEMBL28957503 | 0.68 | SLC6A2 (0.32) | — | |
| SCHEMBL22375273 | 0.67 | — | — | |
| SCHEMBL25272121 | 0.67 | SLC6A2 (0.34) | — | |
| SCHEMBL23555209 | 0.65 | USP2 (0.34) | — | |
| SCHEMBL24176427 | 0.64 | SLC6A9 (0.38) | — | |
| SCHEMBL22375268 | 0.64 | CHRM2 (0.33) | — | |
| SCHEMBL25649720 | 0.64 | LMNA (0.32) | — | |
| SCHEMBL26892677 | 0.63 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228512-A1 | ACYCLIC OXAZEPINE COMPOUNDS COMPRISING A 6-AZA MOIETY AND USES THEREOF | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |