SCHEMBL293357

SCHEMBL293357

CCCCCCc1ccc(N)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.47
MAPT P10636 3/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TLR8 Q9NR97 9/20 0.44
PARP1 P09874 1/20 0.43
CHEK1 O14757 1/20 0.43
NEK2 P51955 1/20 0.43
LIMK1 P53667 1/20 0.43
DYRK1A Q13627 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
TYR P14679 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5748550 1.00 LIPG (0.47) LIPGMAPTCYP3A4KDM4EUSP2
SCHEMBL1668443 1.00 LIPG (0.47) LIPGMAPTCYP3A4KDM4EUSP2
SCHEMBL28931216 0.93 TLR8 (0.44) MAPTCYP3A4KDM4EUSP2ALDH1A1
SCHEMBL5745523 0.89 TLR8 (0.50) LIPGCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL30217449 0.89 TLR8 (0.50) LIPGCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL5748397 0.89 TLR8 (0.50) LIPGCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL5745315 0.89 TLR8 (0.50) LIPGCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL11779245 0.89 LIPG (0.57) LIPGMAPTCYP3A4KDM4EUSP2
SCHEMBL30537736 0.89 LIPG (0.57) LIPGMAPTCYP3A4KDM4EUSP2
SCHEMBL3677393 0.87 LIPG (0.53) LIPGMAPTCYP3A4KDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11479632-B2 Polymer film, method of preparing the same, and flexible folding panel WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-10-25 US claimed
US-20210332186-A1 POLYMER FILM, METHOD OF PREPARING THE SAME, AND FLEXIBLE FOLDING PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US claimed
CN-110607068-B Polymer film, preparation method thereof and flexible folding panel 武汉华星光电半导体显示技术有限公司 2021-03-16 CN claimed
WO-2021031359-A1 POLYMER FILM, PREPARATION METHOD THEREFOR AND FLEXIBLE FOLDING PANEL 武汉华星光电半导体显示技术有限公司 2021-02-25 WO claimed
CN-110607068-A Polymer film, preparation method thereof and flexible folding panel 武汉华星光电半导体显示技术有限公司 2019-12-24 CN claimed
US-11479632-B2 Polymer film, method of preparing the same, and flexible folding panel WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-10-25 US disclosed
US-20210332186-A1 POLYMER FILM, METHOD OF PREPARING THE SAME, AND FLEXIBLE FOLDING PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US disclosed
US-20210332186-A1 POLYMER FILM, METHOD OF PREPARING THE SAME, AND FLEXIBLE FOLDING PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US disclosed
CN-110607068-B Polymer film, preparation method thereof and flexible folding panel 武汉华星光电半导体显示技术有限公司 2021-03-16 CN disclosed
WO-2021031359-A1 POLYMER FILM, PREPARATION METHOD THEREFOR AND FLEXIBLE FOLDING PANEL 武汉华星光电半导体显示技术有限公司 2021-02-25 WO disclosed
CN-110607068-A Polymer film, preparation method thereof and flexible folding panel 武汉华星光电半导体显示技术有限公司 2019-12-24 CN disclosed
US-20140031334-A1 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2014-01-30 US disclosed
EP-2287162-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders Otsuka Pharmaceutical Co., Ltd. (JP) 2011-02-23 EP disclosed
EP-2284169-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders Otsuka Pharmaceutical Co., Limited (JP) 2011-02-16 EP disclosed
US-20090264404-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-10-22 US disclosed
CN-101258147-A 4-piperazin-1-yl-4-benzo [ B ] thiophene derivatives for the treatment of CNS disorders OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031334-A1 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS GRIN2C, GRIN2B, PMP22 LIPG 4852/4885MAPT 223/4885CYP3A4 324/4885
US-20090264404-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders GRIN2C, GRIN2B, PMP22 LIPG 4852/4885MAPT 223/4885CYP3A4 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.