Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217449 | 1.00 | TLR8 (0.50) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL5745523 | 1.00 | TLR8 (0.50) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL5745315 | 1.00 | TLR8 (0.50) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL1668443 | 0.89 | LIPG (0.47) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL5748550 | 0.89 | LIPG (0.47) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL293357 | 0.89 | LIPG (0.47) | TLR8PARP1LIPGALDH1A1CYP3A4 | |
| SCHEMBL22256360 | 0.85 | ALDH1A1 (0.54) | TLR8PARP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL15345634 | 0.84 | TLR8 (0.51) | TLR8LIPGBIDMCL1BCL2L1 | |
| SCHEMBL15345378 | 0.84 | TLR8 (0.51) | TLR8LIPGBIDMCL1BCL2L1 | |
| SCHEMBL23405652 | 0.83 | TLR8 (0.46) | TLR8PARP1LIPGBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |