Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055019 | 0.91 | MAPT (0.82) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL1844199 | 0.91 | MAPT (0.82) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL5669873 | 0.91 | MAPT (0.82) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL25074068 | 0.86 | MAPT (0.53) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL22783768 | 0.85 | MAPT (0.74) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL10055033 | 0.84 | LMNA (0.61) | MAPTGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL6419238 | 0.84 | LMNA (0.61) | MAPTGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL8345852 | 0.84 | MAPT (0.72) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL8348682 | 0.84 | MAPT (0.72) | MAPTGAARAB9AL3MBTL1NPC1 | |
| SCHEMBL169696 | 0.84 | MAPT (0.72) | MAPTGAARAB9AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |