Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519108 | 0.81 | PDK2 (0.55) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL1223198 | 0.81 | PDK2 (0.55) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL11829 | 0.79 | MEN1 (0.52) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL29502068 | 0.79 | MEN1 (0.52) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL31440532 | 0.79 | MEN1 (0.52) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL25255334 | 0.79 | MEN1 (0.46) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL31220002 | 0.76 | MEN1 (0.44) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL22128204 | 0.76 | MEN1 (0.47) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL12742988 | 0.76 | MEN1 (0.44) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL30847461 | 0.76 | MEN1 (0.50) | MEN1KMT2ACMA1AHRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148191-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |