Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 14/20 | 0.55 |
| ▸ | TAS2R8 | Q9NYW2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940720 | 0.87 | IGF1R (0.42) | IGF1RTAS2R8 | |
| SCHEMBL2941315 | 0.85 | IGF1R (0.64) | IGF1RTAS2R8 | |
| SCHEMBL2933712 | 0.84 | IGF1R (0.57) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2939817 | 0.84 | IGF1R (0.36) | IGF1RTAS2R8LMNAMAPK1HTT | |
| SCHEMBL2938532 | 0.83 | IGF1R (0.65) | IGF1R | |
| SCHEMBL2940646 | 0.82 | IGF1R (0.55) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2932317 | 0.82 | IGF1R (0.60) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2940724 | 0.81 | IGF1R (0.64) | IGF1R | |
| SCHEMBL2939922 | 0.81 | IGF1R (0.59) | IGF1R | |
| SCHEMBL2939189 | 0.81 | IGF1R (0.64) | IGF1RTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |