Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.77 |
| ▸ | AXL | P30530 | 8/20 | 0.67 |
| ▸ | CDK8 | P49336 | 3/20 | 0.67 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.64 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.60 |
| ▸ | SGK1 | O00141 | 2/20 | 0.58 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 2/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987950 | 1.00 | RIPK1 (0.77) | RIPK1AXLCDK8TNIKDYRK1A | |
| SCHEMBL29337212 | 0.84 | RIPK1 (0.60) | RIPK1AXLCDK8TNIKDYRK1A | |
| SCHEMBL30987941 | 0.84 | RIPK1 (0.60) | RIPK1AXLCDK8TNIKDYRK1A | |
| SCHEMBL8941685 | 0.81 | AXL (1.00) | AXLCDK8TNIKDYRK1ADYRK1B | |
| SCHEMBL22971829 | 0.81 | TNIK (0.73) | TNIKIGF1RSGK1NTRK1AURKA | |
| SCHEMBL7111817 | 0.79 | AXL (0.60) | RIPK1AXLCDK8TNIKDYRK1A | |
| SCHEMBL8320028 | 0.79 | AXL (0.78) | RIPK1AXLCDK8TNIKIGF1R | |
| SCHEMBL3759420 | 0.79 | AXL (1.00) | RIPK1AXLCDK8TNIKDYRK1A | |
| SCHEMBL1857492 | 0.78 | AXL (0.76) | RIPK1AXLCDK8TNIKIGF1R | |
| SCHEMBL3761281 | 0.78 | AXL (0.76) | RIPK1AXLCDK8TNIKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239795-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239795-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | AXL, ABL1, ZC3HAV1 | RIPK1 85/4885AXL 1/4885CDK8 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.