Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29337232 | 0.79 | DYRK1A (0.33) | DYRK1AHTTKMT2A | |
| SCHEMBL29337254 | 0.79 | — | — | |
| SCHEMBL29875744 | 0.75 | ALDH1A1 (0.42) | HTT | |
| SCHEMBL16415969 | 0.73 | HTT (0.34) | DYRK1AHTTKMT2A | |
| SCHEMBL15595083 | 0.71 | DYRK1A (0.32) | DYRK1A | |
| SCHEMBL25218349 | 0.69 | MAOA (0.38) | DYRK1AHTTKMT2A | |
| SCHEMBL29915220 | 0.69 | MAOA (0.38) | DYRK1AHTTKMT2A | |
| SCHEMBL29337519 | 0.68 | — | — | |
| SCHEMBL15290415 | 0.68 | HTT (0.39) | DYRK1AHTTKMT2A | |
| SCHEMBL17802101 | 0.67 | METAP1 (0.49) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148191-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |