Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280754 | 0.85 | ADRA2A (0.45) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL6280768 | 0.85 | ADRA2A (0.45) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL18713176 | 0.82 | ADRA2A (0.41) | ADRA2AADRA1ACYP2D6CHRM2CHRM1 | |
| SCHEMBL20256745 | 0.82 | ADRA2A (0.46) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL20738509 | 0.81 | CYP2D6 (0.41) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL5663457 | 0.81 | ADRA1A (0.60) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL19578674 | 0.81 | CYP2D6 (0.41) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL2823287 | 0.80 | CYP2D6 (0.53) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL20238552 | 0.80 | CYP2D6 (0.53) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL3702003 | 0.80 | CYP2D6 (0.53) | ADRA2AADRA1ACYP2D6MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |