Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 4/20 | 0.41 |
| ▸ | F11 | P03951 | 4/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18765845 | 0.98 | KMT2A (0.43) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| Hydrochloric Acid SCHEMBL29676660 | 0.98 | KMT2A (0.43) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| Hydrochloric Acid SCHEMBL18765843 | 0.98 | KMT2A (0.43) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| SCHEMBL22952702 | 0.83 | KMT2A (0.40) | KMT2ASMN1; SMN2KCNJ5KCNJ3MEP1B | |
| SCHEMBL22952765 | 0.82 | SCN4A (0.42) | KMT2ASMN1; SMN2MEP1BDRD1ANPEP | |
| SCHEMBL22965296 | 0.82 | SCN4A (0.42) | KMT2ASMN1; SMN2MEP1BDRD1ANPEP | |
| Hydrochloric Acid SCHEMBL28700399 | 0.82 | KMT2A (0.40) | KMT2ASMN1; SMN2KCNJ5KCNJ3MEP1B | |
| SCHEMBL22952665 | 0.82 | KMT2A (0.40) | KMT2ASMN1; SMN2KCNJ5KCNJ3MEP1B | |
| Hydrochloric Acid SCHEMBL28700400 | 0.82 | KMT2A (0.40) | KMT2ASMN1; SMN2KCNJ5KCNJ3MEP1B | |
| Hydrochloric Acid SCHEMBL29440415 | 0.82 | KMT2A (0.40) | KMT2ASMN1; SMN2KCNJ5KCNJ3MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |