Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A15 | Q9H2J7 | 3/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068898 | 0.79 | NOTUM (0.59) | SLC6A15FNTAFNTBNOTUMMCHR1 | |
| SCHEMBL29338248 | 0.78 | MAPT (0.46) | MEN1 | |
| SCHEMBL29338289 | 0.78 | ESR1 (0.56) | NOTUMSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2585109 | 0.75 | ESR1 (0.62) | ERCC1ERCC4NOTUMHTR2AHTR2C | |
| SCHEMBL6306088 | 0.75 | MCHR1 (0.55) | SLC6A15NOTUMMCHR1POLBHPGD | |
| SCHEMBL29390456 | 0.74 | ESR1 (0.50) | ERCC1ERCC4NOTUMPOLBHPGD | |
| SCHEMBL13623452 | 0.74 | ESR1 (0.50) | ERCC1ERCC4NOTUMPOLBHPGD | |
| SCHEMBL5539399 | 0.74 | ESR2 (0.54) | ERCC1ERCC4NOTUMPOLBHPGD | |
| SCHEMBL8221038 | 0.73 | NOTUM (0.63) | ERCC1ERCC4NOTUMMCHR1TAS1R3 | |
| SCHEMBL10920943 | 0.73 | NOTUM (0.63) | ERCC1ERCC4NOTUMMCHR1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |