Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 5/20 | 0.51 |
| ▸ | DRD5 | P21918 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351344 | 0.82 | ESR1 (0.62) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL11455526 | 0.81 | KMT2A (0.66) | ESR1ESR2DRD1DRD5DRD2 | |
| SCHEMBL3157287 | 0.81 | ESR1 (0.52) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL12209611 | 0.78 | MTNR1B (0.60) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL10400059 | 0.78 | ESR1 (0.64) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL29338249 | 0.78 | SLC6A15 (0.54) | NOTUMMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11457061 | 0.77 | MTNR1B (0.64) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL2309023 | 0.77 | ESR1 (0.85) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL3150165 | 0.77 | RYR2 (0.58) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL521554 | 0.77 | KMT2A (0.48) | MEN1KMT2AABCB1ABCC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |