Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343855 | 0.81 | ALDH1A1 (0.61) | ALDH1A1EPHX1ALOX15POLB | |
| SCHEMBL25196101 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CPN1CPB2ARG1ALOX15 | |
| SCHEMBL26775909 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CPN1CPB2ARG1ALOX15 | |
| SCHEMBL20738498 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1EPHX1 | |
| SCHEMBL21834363 | 0.76 | EPHX1 (0.37) | ALDH1A1EPHX1 | |
| SCHEMBL30782076 | 0.71 | USP2 (0.39) | ALDH1A1EPHX1 | |
| Hydrochloric Acid SCHEMBL26643833 | 0.70 | DPP4 (0.38) | ALDH1A1CPN1CPB2ARG1POLB | |
| SCHEMBL13438125 | 0.68 | CPN1 (0.39) | ALDH1A1CPN1CPB2 | |
| SCHEMBL8669350 | 0.68 | ALDH1A1 (0.40) | ALDH1A1CPN1CPB2ARG1POLB | |
| SCHEMBL18793808 | 0.67 | LMNA (0.49) | ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |