Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 8/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29340826 | 0.92 | CFD (0.43) | CFDICMTSCN9ATBXAS1MEN1 | |
| SCHEMBL29122344 | 0.91 | CFD (0.40) | CFDICMTTBXAS1MEN1POLB | |
| SCHEMBL29340886 | 0.91 | CFD (0.43) | CFDICMTSCN9ATBXAS1MEN1 | |
| SCHEMBL29339704 | 0.91 | CFD (0.46) | CFDICMT | |
| SCHEMBL29344014 | 0.91 | P2RX3 (0.36) | CFDICMTHPGDKMT2ASYK | |
| SCHEMBL29340323 | 0.91 | CFD (0.42) | CFDICMTSCN9ATBXAS1SYK | |
| SCHEMBL23218313 | 0.90 | CFD (0.49) | CFDICMTSCN9ATBXAS1MEN1 | |
| SCHEMBL29852743 | 0.90 | CFD (0.49) | CFDICMTSCN9ATBXAS1MEN1 | |
| SCHEMBL29340880 | 0.90 | CFD (0.42) | CFDICMTSCN9ATBXAS1MEN1 | |
| SCHEMBL29122004 | 0.86 | CFD (0.42) | CFDICMTTBXAS1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | CFD 3529/4885ICMT 4826/4885SCN9A 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.