4-Nitroaniline

4-Nitroaniline

SCHEMBL2934038

CC(C)CC(N)C(=O)O.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.53
ALDH1A1 P00352 1/20 0.53
GRIK1 P39086 1/20 0.52
GRIK2 Q13002 1/20 0.52
KMO O15229 1/20 0.47
ESR1 P03372 2/20 0.47
CYP19A1 P11511 2/20 0.47
ESR2 Q92731 2/20 0.47
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRM4 Q14833 1/20 0.46
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.44
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
PTPRA P18433 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
SLC1A1 P43005 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitroaniline SCHEMBL10773363 1.00 SLC7A5 (0.53) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL2934041 1.00 SLC7A5 (0.53) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL11139552 1.00 SLC7A5 (0.53) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL27907952 0.99 SLC7A5 (0.51) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL28723261 0.96 GRIK1 (0.49) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL9278097 0.89 GRM8 (0.44) SLC7A5ALDH1A1GRIK1GRIK2KMO
Leucine SCHEMBL29071569 0.88 SLC7A5 (0.56) SLC7A5ALDH1A1GRIK1GRIK2KMO
4-Nitroaniline SCHEMBL3264895 0.84 ALDH1A1 (0.64) ALDH1A1ESR1CYP19A1ESR2KMT2A
4-Nitroaniline SCHEMBL5974424 0.84 ALDH1A1 (0.64) ALDH1A1ESR1CYP19A1ESR2KMT2A
4-Nitroaniline SCHEMBL10711921 0.84 ALDH1A1 (0.64) ALDH1A1ESR1CYP19A1ESR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114958962-A Response determination method for wheat root activity, rhizosphere soil enzyme activity and microbial community diversity 河南省农业科学院植物营养与资源环境研究所 2022-08-30 CN claimed
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 CN claimed
US-12208118-B2 Pharmaceutical compositions for delivery of peptide ANYA BIOPHARM INC. (CN) 2025-01-28 US disclosed
CN-119144694-A Enzyme activity detection method of aminopeptidase 武汉新华扬生物股份有限公司 2024-12-17 CN disclosed
CN-119144694-A Enzyme activity detection method of aminopeptidase 武汉新华扬生物股份有限公司 2024-12-17 CN disclosed
CN-118165961-A Preparation method and application of novel halophilic archaea aminopeptidase 江苏大学 2024-06-11 CN disclosed
CN-116064280-B Siamese bacillus and application thereof 大连工业大学 2024-05-07 CN disclosed
CN-116004423-B Bacillus bailii and application thereof 大连工业大学 2024-05-07 CN disclosed
CN-116064279-B Siamese bacillus and application thereof in low-salt fermentation of food 大连工业大学 2024-04-02 CN disclosed
CN-116004424-B Bacillus tequilensis and application thereof in low-salt fermentation of food 大连工业大学 2024-04-02 CN disclosed
CN-116064279-B Siamese bacillus and application thereof in low-salt fermentation of food 大连工业大学 2024-04-02 CN disclosed
US-7258996-B2 Metalloproteinase inhibitory agent NESTEC S.A. (CH) 2007-08-21 US disclosed
EP-1221954-B1 METHODS FOR IDENTIFYING INHIBITORS OF METHIONINE AMINOPEPTIDASES UNIV SAINT LOUIS (US) 2006-09-13 EP disclosed
US-20050187155-A1 Metalloproteinase inhibitory agent NESETC S.A. (CH) 2005-08-25 US disclosed
EP-1501864-A1 METALLO PROTEINASE INHIBITORY AGENT Société des Produits Nestlé S.A. (CH) 2005-02-02 EP disclosed
WO-2003093308-A1 METALLO PROTEINASE INHIBITORY AGENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 2003-11-13 WO disclosed
EP-1359157-A1 Metallo-proteinase inhibitory agent Société des Produits Nestlé S.A. (CH) 2003-11-05 EP disclosed
CN-1364171-A Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs SEVILLE LAB (FR) 2002-08-14 CN disclosed
US-6261794-B1 COMBINING A SAMPLE WITH A N-TERMINAL METHIONINE PEPTIDE AND A SECOND PEPTIDE WITH A C-TERMINAL DETECTION MOIETY THAT IS RELEASED BY A SECOND PEPTIDASE ONLY IF THE N-TERMINAL PEPTIDE HAS BEEN CLEAVED BY METHIONINE AMINOPEPTIDASE SAINT LOUIS UNIVERSITY 2001-07-17 US disclosed
CN-1230225-A Improved process for prodn. of alcoholic beverages usingmaltsseed MOGEN INT (NL) 1999-09-29 CN disclosed