Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroaniline SCHEMBL5974424 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL3264892 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL10711921 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL29058965 | 0.88 | ALDH1A1 (0.58) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| Nitrobenzene SCHEMBL23406805 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| 4-Nitroaniline SCHEMBL28656726 | 0.85 | ALDH1A1 (0.75) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL1900089 | 0.85 | ALDH1A1 (0.75) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| Dl-Phenylalanine SCHEMBL28464461 | 0.85 | SLC7A5 (0.56) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL11298826 | 0.85 | ALDH1A1 (0.82) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| 4-Nitroaniline SCHEMBL2934038 | 0.84 | SLC7A5 (0.53) | ALDH1A1ESR1CYP19A1ESR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229091-B | 1, 5-disubstituted indole derivatives with leukotriene A4 hydrolase inhibition effect and application thereof | 天津科技大学 | 2022-11-22 | — | — | CN | disclosed |
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2010-03-18 | — | — | US | disclosed |
| EP-1042457-B1 | POLYPEPTIDES HAVING AMINOPEPTIDASE ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVOZYMES AS (DK) | 2006-03-08 | — | — | EP | disclosed |
| US-6673571-B2 | POLYPEPTIDE FOR USE AS TOOLS IN FOOD PROCESSING AND GENETIC ENGINEERING | NOVOZYMES BIOTECH, INC. | 2004-01-06 | — | — | US | disclosed |
| EP-0984703-B1 | METHODS OF PRODUCING PROTEIN HYDROLYSATES | NOVOZYMES BIOTECH INC (US) | 2003-04-09 | — | — | EP | disclosed |
| US-20020177210-A1 | Polypeptides having aminopeptidase activity and nucleic acids encoding same | NOVOZYMES BIOTECH, INC. | 2002-11-28 | — | — | US | disclosed |
| US-6465209-B1 | MIXING WITH AMINOPEPTIDASE WITH GLYCINE RELEASING PROPERTIES; HYDROLYSIS | NOVOZYMES BIOTECH, INC. | 2002-10-15 | — | — | US | disclosed |
| US-6303360-B1 | CULTURING SPHINGOMONAS; MOLECULAR HYBRIDIZATION; GENETIC ENGINEERING; HYDROLYZES ANILIDES OF ALANINE, GLYCINE, LEUCINE, GLUTAMIC ACID, ASPARTIC ACID, LYSINE, ISOLEUCINE, AND VALINE | NOVOZYMES BIOTECH, INC, | 2001-10-16 | — | — | US | disclosed |
| US-6184020-B1 | AMINO ACID AND NUCLEOTIDE SEQUENCE; FOR PRODUCTION OF PROTEIN HYDROLYSATES USED AS FLAVORINGS IN FOODS | NOVO NORDISK BIOTECH, INC. | 2001-02-06 | — | — | US | disclosed |
| EP-1042457-A1 | POLYPEPTIDES HAVING AMINOPEPTIDASE ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK A/S (DK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031226-A1 | POLYPEPTIDES HAVING AMINOPEPTIDASE ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK A/S (DK) | 1999-06-24 | — | — | WO | disclosed |
| US-5780239-A | FORMING AN IMMUNOCOMPLEX WITH A LABELLED ANTIBODY SPECIFICALLY BINDING TO TAMM-HORSFALL PROTEIN; ELISA; DIPSTICKS; SPECTRUM ANALYSIS | CHIMERA RESEARCH AND CHEMICAL INC. | 1998-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | ANPEP, ENPEP, DNPEP | ALDH1A1 549/4885ESR1 2198/4885CYP19A1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.