Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963260 | 0.89 | HSD11B1 (0.39) | HSD11B1CYP2D6 | |
| SCHEMBL9965966 | 0.74 | — | — | |
| SCHEMBL29341677 | 0.73 | CYP2D6 (0.46) | CYP2D6 | |
| SCHEMBL12748276 | 0.72 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL12827763 | 0.72 | CHRNA7 (0.38) | HSD11B1CYP2D6 | |
| SCHEMBL15960718 | 0.70 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL27380449 | 0.70 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL10147397 | 0.69 | L3MBTL1 (0.33) | HSD11B1 | |
| SCHEMBL13697437 | 0.68 | GRIN2D (0.37) | HSD11B1 | |
| SCHEMBL18633580 | 0.68 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239813-A1 | KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239813-A1 | KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF | KRAS, NRAS, HRAS | HSD11B1 2409/4885CYP2D6 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.