Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421127 | 0.83 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8928325 | 0.74 | LAP3 (0.53) | CYP3A4CYP2D6LAP3 | |
| SCHEMBL9309772 | 0.72 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL10979801 | 0.72 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL4074290 | 0.71 | IDO1 (0.43) | CYP3A4CYP2D6LAP3KMT2A | |
| SCHEMBL10714489 | 0.71 | LAP3 (0.51) | LAP3 | |
| SCHEMBL12876206 | 0.69 | LAP3 (0.49) | LAP3 | |
| SCHEMBL12847565 | 0.68 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL9665263 | 0.68 | LAP3 (0.48) | LAP3 | |
| SCHEMBL9667088 | 0.68 | LAP3 (0.48) | LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501398-B2 | Luminescence assay using macrocyclic lanthanide (III) complexes | UNIVERSITY OF DURHAM (GB) | 2013-08-06 | — | — | US | disclosed |
| EP-2041571-B1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIV DURHAM (GB) | 2010-09-15 | — | — | EP | disclosed |
| US-20100055665-A1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2010-03-04 | — | — | US | disclosed |
| EP-2041571-A1 | LUMINEESCENCE ASSAY USING MACROCYCLIC LANTHANIDE ( III ) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008007089-A1 | LUMINEESCENCE ASSAY USING MACROCYCLIC LANTHANIDE ( III ) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2008-01-17 | — | — | WO | disclosed |