Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23347485 | 1.00 | CYP2C9 (0.30) | CYP2C9TSHRCYP2C19TDP1NOS3 | |
| SCHEMBL22680724 | 1.00 | — | — | |
| SCHEMBL11522682 | 1.00 | — | — | |
| SCHEMBL23222175 | 1.00 | — | — | |
| SCHEMBL19309258 | 0.97 | CYP2C9 (0.32) | CYP2C9TSHRCYP2C19TDP1NOS3 | |
| SCHEMBL6396771 | 0.94 | THRB (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL22340337 | 0.94 | THRB (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL13697414 | 0.94 | CYP2C9 (0.33) | CYP2C9TSHRCYP2C19TDP1NOS3 | |
| SCHEMBL18616053 | 0.94 | CYP2C9 (0.33) | CYP2C9TSHRCYP2C19TDP1NOS3 | |
| SCHEMBL13697412 | 0.94 | CYP2C9 (0.33) | CYP2C9TSHRCYP2C19TDP1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | CYP2C9 825/4885TSHR 4825/4885CYP2C19 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.