Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344000 | 0.82 | OPRK1 (0.41) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29344015 | 0.79 | CYP2B6 (0.35) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29937454 | 0.76 | OPRK1 (0.38) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29344016 | 0.72 | RORC (0.49) | — | |
| SCHEMBL29937033 | 0.65 | SSTR4 (0.36) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29343999 | 0.65 | SSTR4 (0.36) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29344003 | 0.64 | OPRK1 (0.34) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL29344018 | 0.64 | SSTR4 (0.40) | CYP2B6OPRK1KCNH2CHRM3CHRM2 | |
| SCHEMBL6620254 | 0.63 | CHRM2 (0.46) | CHRM3CHRM2CHRM1CHRM4MAPK1 | |
| SCHEMBL6620257 | 0.63 | CHRM2 (0.46) | CHRM3CHRM2CHRM1CHRM4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | CYP2B6 4108/4885OPRK1 4635/4885KCNH2 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.