Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862971 | 0.85 | CLCN2 (0.43) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL19380553 | 0.82 | GABRA1 (0.42) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL8995207 | 0.80 | CLCN2 (0.40) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL8814289 | 0.80 | CLCN2 (0.40) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL8814283 | 0.80 | CLCN2 (0.40) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL14424505 | 0.79 | ALDH1A1 (0.48) | TSHRALDH1A1TP53HPGDHDAC3 | |
| SCHEMBL11412880 | 0.79 | GABRA1 (0.44) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL2935940 | 0.78 | GABRA1 (0.48) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL7987828 | 0.77 | CLCN2 (0.38) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL7991056 | 0.77 | NPSR1 (0.39) | CLCN2GABRA1GABRB2TSHRF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632910-B1 | 3,4-DIHYDROQUINOLINONES AS FXR RECEPTOR AGONISTS | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |