Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344706 | 0.83 | CDK2 (0.37) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL24964837 | 0.83 | CDK2 (0.36) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL1370649 | 0.81 | CDK2 (0.40) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL13650606 | 0.69 | ALDH1A1 (0.44) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL5119212 | 0.68 | PDE10A (0.40) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL12953072 | 0.68 | PDE10A (0.46) | CDK2PDE10AKDM4ERAB9AALDH1A1 | |
| SCHEMBL20971704 | 0.67 | MAPT (0.54) | CDK2KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL26974008 | 0.67 | CDK2 (0.40) | CDK2KDM4EALDH1A1MAPTGSK3B | |
| SCHEMBL17625103 | 0.67 | CDK2 (0.40) | CDK2GSK3B | |
| SCHEMBL23181597 | 0.66 | KDM4E (0.40) | CDK2KDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |