Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | CCNH | P51946 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | INSRR | P14616 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24964837 | 0.85 | CDK2 (0.36) | CDK2CDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL29344761 | 0.83 | CDK2 (0.35) | CDK2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL1370649 | 0.83 | CDK2 (0.40) | CDK2CDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL29344675 | 0.72 | ALDH1A1 (0.34) | CDK2CDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL29344742 | 0.71 | HSP90AA1 (0.33) | KDM4EMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL29344733 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL13650606 | 0.71 | ALDH1A1 (0.44) | CDK2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL5119212 | 0.70 | PDE10A (0.40) | CDK2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12953072 | 0.70 | PDE10A (0.46) | CDK2CDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL20971704 | 0.69 | MAPT (0.54) | CDK2CDK5CDK5R1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |