SCHEMBL2934622

SCHEMBL2934622

CCCCCCCC/C=C\CCCCCCCCOC[C@@H](O)COP(=O)(O)O

nearest known ligand 0.83

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LPAR5 Q9H1C0 4/20 0.83
▸ P2RY10 O00398 1/20 0.69
▸ LPAR1 Q92633 13/20 0.67
▸ LPAR3 Q9UBY5 11/20 0.67
▸ LPAR2 Q9HBW0 6/20 0.67
▸ LPAR4 Q99677 3/20 0.67
▸ ENPP2 Q13822 2/20 0.67
▸ LPAR6 P43657 2/20 0.67
▸ CES2 O00748 1/20 0.67
▸ TRPV1 Q8NER1 1/20 0.67
▸ S1PR4 O95977 2/20 0.56
▸ S1PR1 P21453 2/20 0.56
▸ S1PR3 Q99500 2/20 0.56
▸ S1PR5 Q9H228 2/20 0.56
▸ S1PR2 O95136 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ TSPO P30536 1/20 0.56
▸ TMEM97 Q5BJF2 1/20 0.56
▸ SIGMAR1 Q99720 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4623591 1.00 LPAR5 (0.83) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258081 1.00 LPAR5 (0.83) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL12621099 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258094 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL7820593 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258161 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258118 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL7829804 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258032 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL26603866 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577554-B2 Gas-filled stabilized particles and methods of use CHILDREN'S MEDICAL CENTER CORPORATION (US) 2020-03-03 — — US disclosed
US-20160030596-A1 GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-02-04 — — US disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160030596-A1 GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE LIPA, PPARG, LPXN LPAR5 354/4885P2RY10 1649/4885LPAR1 442/4885
US-10577554-B2 Gas-filled stabilized particles and methods of use LIPA, PPARG, LPXN LPAR5 354/4885P2RY10 1649/4885LPAR1 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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