SCHEMBL4623591

SCHEMBL4623591

CCCCCCCC/C=C\CCCCCCCCCCCCOCC(O)COP(=O)(O)O

nearest known ligand 0.83

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LPAR5 Q9H1C0 4/20 0.83
▸ P2RY10 O00398 1/20 0.69
▸ LPAR1 Q92633 13/20 0.67
▸ LPAR3 Q9UBY5 11/20 0.67
▸ LPAR2 Q9HBW0 6/20 0.67
▸ LPAR4 Q99677 3/20 0.67
▸ ENPP2 Q13822 2/20 0.67
▸ LPAR6 P43657 2/20 0.67
▸ CES2 O00748 1/20 0.67
▸ TRPV1 Q8NER1 1/20 0.67
▸ S1PR4 O95977 2/20 0.56
▸ S1PR1 P21453 2/20 0.56
▸ S1PR3 Q99500 2/20 0.56
▸ S1PR5 Q9H228 2/20 0.56
▸ S1PR2 O95136 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ TSPO P30536 1/20 0.56
▸ TMEM97 Q5BJF2 1/20 0.56
▸ SIGMAR1 Q99720 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2934622 1.00 LPAR5 (0.83) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258081 1.00 LPAR5 (0.83) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL12621099 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258094 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL7820593 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258161 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258118 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL7829804 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL258032 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2
SCHEMBL26603866 0.91 LPAR5 (1.00) LPAR5P2RY10LPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673424-B1 DNA ENCODING 2-ACYLTRANSFERASES BIOGEMMA UK LTD (GB) 2008-05-21 — — EP disclosed
US-6583340-B2 DNA sequence; transgenic plants; enzyme preferentially produces erucic acid triglycerides such as trierucin; vegetable oil GENE SHEARS PTY. LIMITED (AU) 2003-06-24 — — US disclosed
US-20020007499-A1 DNA SEQUENCE ENCODING PLANT 2-ACYLTRANSFERASE GENE SHEARS PTY. LIMITED (AU) 2002-01-17 — — US disclosed
US-6194640-B1 Plant expressing 2-acyltransferase BIOGEMMA UK LIMITED (GB) 2001-02-27 — — US disclosed
US-5945323-A AMINO ACID SEQUENCE OF PLANT ENZYME; PROBES TO SCREEN LIBRARIES; FOR PRODUCTION OF TRANSGENIC PLANTS TO INCREASE ERUCIC ACID CONTENT OF OIL PRODUCED BIOGEMMA UK LIMITED (GB) 1999-08-31 — — US disclosed
US-5843739-A DNA encoding 2-acyltransferases NICKERSON BIOCEM LIMITED (GB) 1998-12-01 — — US disclosed
EP-0808368-A1 DNA SEQUENCE ENCODING PLANT 2-ACYLTRANSFERASE Gene Shears Pty Limited (AU) 1997-11-26 — — EP disclosed
WO-1996024674-A1 DNA SEQUENCE ENCODING PLANT 2-ACYLTRANSFERASE GENE SHEARS PTY. LIMITED (AU) 1996-08-15 — — WO disclosed
EP-0673424-A1 DNA ENCODING 2-ACYLTRANSFERASES NICKERSON BIOCEM LIMITED (GB) 1995-09-27 — — EP disclosed
WO-1994013814-A1 DNA ENCODING 2-ACYLTRANSFERASES NICKERSON BIOCEM LIMITED (GB) 1994-06-23 — — WO disclosed
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