Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29347141 | 0.88 | PSEN1 (0.35) | ADORA2AADORA1MKNK1MKNK2ALDH1A1 | |
| SCHEMBL29346446 | 0.82 | CRBN (0.45) | PARP1ALDH1A1 | |
| SCHEMBL21946654 | 0.79 | CRBN (0.53) | ALDH1A1 | |
| SCHEMBL26138573 | 0.77 | CRBN (0.40) | PARP1NSD3ALDH1A1 | |
| SCHEMBL29347226 | 0.75 | ALDH1A1 (0.42) | PARP1ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL29347046 | 0.72 | PARP1 (0.37) | PARP1ADORA2AADORA1MKNK1MKNK2 | |
| SCHEMBL29347145 | 0.71 | CRBN (0.39) | ALDH1A1 | |
| SCHEMBL29346392 | 0.70 | DDB1 (0.61) | MKNK1MKNK2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL24891103 | 0.69 | CRBN (0.47) | ALDH1A1 | |
| SCHEMBL31730204 | 0.68 | MKNK1 (0.40) | PARP1MKNK1MKNK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |