Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29347228 | 0.81 | CRBN (0.48) | ALDH1A1DPP4DPP8DPP9SRC | |
| SCHEMBL19586591 | 0.78 | CRBN (0.53) | ALDH1A1DPP4DPP8DPP9DDB1 | |
| SCHEMBL29346443 | 0.75 | PARP1 (0.39) | ALDH1A1KDM4EADORA2AADORA1PARP1 | |
| SCHEMBL31730204 | 0.70 | MKNK1 (0.40) | ALDH1A1KDM4EDDB1CRBNPARP1 | |
| SCHEMBL29347046 | 0.69 | PARP1 (0.37) | ALDH1A1KDM4EDDB1CRBNADORA2A | |
| SCHEMBL14500140 | 0.68 | DPP4 (0.49) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL3125601 | 0.67 | CRBN (0.55) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL18263933 | 0.67 | CRBN (0.55) | ALDH1A1KDM4EDDB1CRBNMAPT | |
| SCHEMBL18263920 | 0.66 | CRBN (0.56) | ALDH1A1KDM4ECRBNGAAMAPT | |
| SCHEMBL3493499 | 0.66 | ALDH1A1 (0.40) | ALDH1A1CNR1KDM4EDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |