Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346391 | 0.86 | CHRM1 (0.53) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL31730155 | 0.86 | CHRM1 (0.53) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL29346538 | 0.81 | CRBN (0.52) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL26092381 | 0.77 | OPRL1 (0.86) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL30910142 | 0.77 | OPRL1 (0.86) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL2217118 | 0.75 | OPRM1 (0.74) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL12028946 | 0.73 | OPRM1 (0.67) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL29346392 | 0.73 | DDB1 (0.61) | KDM4EALDH1A1 | |
| SCHEMBL853223 | 0.72 | OPRM1 (1.00) | OPRL1OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL1271556 | 0.70 | OPRM1 (1.00) | OPRL1OPRM1OPRK1OPRD1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |