Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610075 | 0.89 | MAPT (0.57) | MAPTGAALMNAPOLBNAMPT | |
| SCHEMBL30781039 | 0.87 | MAPT (0.58) | MAPTGAALMNAPOLBNAMPT | |
| SCHEMBL2930543 | 0.87 | MAPT (0.58) | MAPTGAALMNAPOLBNAMPT | |
| SCHEMBL23247037 | 0.80 | MAPT (0.50) | MAPTGAALMNAPOLBNAMPT | |
| SCHEMBL28186774 | 0.77 | MAPT (0.53) | MAPTLMNAPOLBALDH1A1MEN1 | |
| SCHEMBL2928230 | 0.75 | NFE2L2 (0.38) | MAPTGAALMNAPOLBALDH1A1 | |
| SCHEMBL7711910 | 0.75 | KDM4E (0.62) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5442441 | 0.73 | NFE2L2 (0.37) | MAPTGAALMNAPOLBALDH1A1 | |
| SCHEMBL6199323 | 0.73 | KAT2B (0.49) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5445415 | 0.72 | MAPT (0.81) | MAPTGAALMNAPOLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739084-B1 | Double para-phenylenediamines joined by a linker comprising a saturated cyclic radical and use thereof as dyeing agents | OREAL (FR) | 2010-09-15 | — | — | EP | disclosed |
| EP-1739084-B1 | Double para-phenylenediamines joined by a linker comprising a saturated cyclic radical and use thereof as dyeing agents | OREAL (FR) | 2010-09-15 | — | — | EP | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739084-A1 | Double para-phenylenediamines joined by a linker comprising a saturated cyclic radical and use thereof as dyeing agents | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | KRT18, CDC73, AOC1 | MAPT 4112/4885GAA 4777/4885LMNA 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.