Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781533 | 0.80 | POLB (0.50) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL28874935 | 0.71 | TERT (0.56) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL4215305 | 0.71 | POLB (0.47) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL28306659 | 0.70 | TERT (0.57) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL3783199 | 0.70 | HDAC1 (0.52) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL17185782 | 0.70 | TP53 (0.46) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL13467825 | 0.70 | PSMD14 (0.44) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL27490086 | 0.70 | POLB (0.43) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL30604184 | 0.69 | HDAC1 (0.45) | TP53POLBPSMD14MMP2CHRNA7 | |
| SCHEMBL22440445 | 0.69 | NCOA3 (0.55) | TP53POLBPSMD14MMP2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |