Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968855 | 0.72 | IRAK4 (0.47) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL3663651 | 0.72 | IRAK4 (0.47) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL6266294 | 0.72 | IRAK4 (0.47) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL27511285 | 0.70 | IRAK4 (0.42) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL21835618 | 0.70 | IRAK4 (0.42) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL20425250 | 0.70 | IRAK4 (0.42) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL4560229 | 0.68 | BCAT2 (0.45) | PARP1AURKARPS6KB1AURKB | |
| SCHEMBL28754510 | 0.67 | CTNNB1 (0.47) | PARP1TP53MAPTSMN1; SMN2 | |
| SCHEMBL3351170 | 0.66 | IRAK4 (0.47) | PARP1MAPTAURKARPS6KB1AURKB | |
| SCHEMBL4786305 | 0.66 | IRAK4 (0.47) | PARP1MAPTAURKARPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313731-B1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | UCB SA (BE) | 2010-09-29 | — | — | EP | disclosed |
| EP-1313731-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002022612-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-21 | — | — | WO | disclosed |