SCHEMBL29347155

SCHEMBL29347155

Cn1c(=O)n(C2CCCCNC2=O)c2cccc(CCCCCCCC(=O)OC(C)(C)C)c21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 2/20 0.34
DDB1 Q16531 2/20 0.32
CRBN Q96SW2 2/20 0.32
CCR2 P41597 4/20 0.32
CCR1 P32246 1/20 0.32
CCR5 P51681 1/20 0.32
CXCR4 P61073 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29347158 0.87 DDB1 (0.44) HTR4DDB1CRBN
SCHEMBL29347182 0.86 DDB1 (0.45) DDB1CRBN
SCHEMBL29347152 0.85 HTR4 (0.32) HTR4DDB1CRBN
SCHEMBL21996675 0.83 DDB1 (0.51) DDB1CRBN
SCHEMBL31068578 0.81 HTR4 (0.39) HTR4DDB1CRBNALDH1A1
SCHEMBL24046568 0.81 DDB1 (0.38) DDB1CRBN
SCHEMBL29347180 0.80 DDB1 (0.47) DDB1CRBN
SCHEMBL26004337 0.79 HTR6 (0.35) DDB1CRBNCCR5
SCHEMBL21997326 0.79 DDB1 (0.53) DDB1CRBN
SCHEMBL21996880 0.78 DDB1 (0.48) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL HTR4 2960/4885DDB1 2368/4885CRBN 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.