SCHEMBL29347427

SCHEMBL29347427

CC(C)(C)OC(=O)NCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 13/20 0.51
▸ CRBN Q96SW2 13/20 0.51
▸ OPRM1 P35372 2/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ OGFRL1 Q5TC84 1/20 0.40
▸ DRD2 P14416 2/20 0.39
▸ CNR2 P34972 1/20 0.39
▸ OPRL1 P41146 1/20 0.38
▸ CAMK2D Q13557 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29347426 0.95 DDB1 (0.51) DDB1CRBNOPRM1OPRD1OPRK1
SCHEMBL31730014 0.93 DDB1 (0.50) DDB1CRBNDRD2CNR2CAMK2D
SCHEMBL31729996 0.91 DDB1 (0.58) DDB1CRBNOPRM1OPRD1OPRK1
SCHEMBL20850714 0.87 DDB1 (0.63) DDB1CRBN
SCHEMBL31068515 0.84 DDB1 (0.51) DDB1CRBNOPRM1OPRL1
SCHEMBL29347429 0.83 DDB1 (0.48) DDB1CRBNOPRM1OPRL1
SCHEMBL29347124 0.83 DDB1 (0.47) DDB1CRBNOPRM1OPRL1
SCHEMBL31068572 0.82 DDB1 (0.55) DDB1CRBN
SCHEMBL29346456 0.80 DDB1 (0.60) DDB1CRBNOPRM1OPRD1OPRK1
SCHEMBL31730022 0.79 CRBN (0.50) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 — — EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 — — WO disclosed
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