SCHEMBL31729996

SCHEMBL31729996

CC(C)(C)OC(=O)NCCOCCOCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 10/20 0.58
▸ CRBN Q96SW2 10/20 0.58
▸ OPRM1 P35372 1/20 0.38
▸ OPRD1 P41143 1/20 0.38
▸ OPRK1 P41145 1/20 0.38
▸ OGFRL1 Q5TC84 1/20 0.38
▸ BCHE P06276 1/20 0.37
▸ CNR2 P34972 1/20 0.37
▸ CNR1 P21554 1/20 0.37
▸ STAT3 P40763 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850714 0.96 DDB1 (0.63) DDB1CRBNSTAT3
SCHEMBL29347427 0.91 DDB1 (0.51) DDB1CRBNOPRM1OPRD1OPRK1
SCHEMBL29347426 0.90 DDB1 (0.51) DDB1CRBNOPRM1OPRD1OPRK1
SCHEMBL31730014 0.88 DDB1 (0.50) DDB1CRBNCNR2
SCHEMBL20840369 0.83 DDB1 (0.52) DDB1CRBNSTAT3
SCHEMBL20850806 0.80 CRBN (0.57) DDB1CRBN
SCHEMBL31068515 0.80 DDB1 (0.51) DDB1CRBNOPRM1
SCHEMBL26098558 0.79 DDB1 (0.59) DDB1CRBNSTAT3
SCHEMBL26100785 0.79 DDB1 (0.59) DDB1CRBNSTAT3
SCHEMBL26504792 0.79 DDB1 (0.59) DDB1CRBNSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 — — EP disclosed
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