SCHEMBL29347429

SCHEMBL29347429

CC(C)(C)OC(=O)CCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 15/20 0.48
▸ CRBN Q96SW2 15/20 0.48
▸ CACNA1G O43497 2/20 0.38
▸ CACNA1H O95180 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ HTR4 Q13639 1/20 0.37
▸ OPRM1 P35372 1/20 0.36
▸ OPRL1 P41146 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29347124 0.99 DDB1 (0.47) DDB1CRBNCACNA1GCACNA1HKDM4E
SCHEMBL28649449 0.94 DDB1 (0.53) DDB1CRBNCACNA1GCACNA1HKDM4E
SCHEMBL31068515 0.88 DDB1 (0.51) DDB1CRBNKDM4EALDH1A1OPRM1
SCHEMBL31068531 0.87 DDB1 (0.45) DDB1CRBNKDM4EALDH1A1
SCHEMBL31730014 0.86 DDB1 (0.50) DDB1CRBN
SCHEMBL29347426 0.85 DDB1 (0.51) DDB1CRBNOPRM1
SCHEMBL31068578 0.85 HTR4 (0.39) DDB1CRBNCACNA1GCACNA1HKDM4E
SCHEMBL29347427 0.83 DDB1 (0.51) DDB1CRBNOPRM1OPRL1
SCHEMBL29347122 0.83 HTR4 (0.40) CACNA1GCACNA1HKDM4EALDH1A1HTR4
SCHEMBL24269179 0.82 DDB1 (0.48) DDB1CRBNHTR4OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 — — EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 — — WO disclosed
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