Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346751 | 0.82 | OPRM1 (0.35) | OPRM1OPRD1OPRK1GAAPKLR | |
| SCHEMBL23108902 | 0.82 | KDM4E (0.35) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL12464308 | 0.78 | OPRM1 (0.35) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL27276592 | 0.77 | OPRM1 (0.35) | OPRM1OPRD1OPRK1PKLR | |
| SCHEMBL12673901 | 0.76 | KDM4E (0.39) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL5064559 | 0.76 | DPP4 (0.33) | — | |
| SCHEMBL25045011 | 0.76 | CYP2D6 (0.33) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL23442163 | 0.74 | KDM4E (0.46) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL14400310 | 0.72 | KDM4E (0.37) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL10643969 | 0.72 | KDM4E (0.41) | OPRM1OPRD1OPRK1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |