Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348129 | 0.82 | OPRM1 (0.37) | OPRM1OPRD1OPRK1GAAPKLR | |
| SCHEMBL27276592 | 0.79 | OPRM1 (0.35) | OPRM1OPRD1OPRK1PKLR | |
| SCHEMBL14031186 | 0.78 | GAA (0.38) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL5064559 | 0.78 | DPP4 (0.33) | — | |
| SCHEMBL22309865 | 0.77 | GAA (0.33) | OPRM1GAAMAPK1 | |
| SCHEMBL12464686 | 0.77 | OPRM1 (0.33) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL12464685 | 0.75 | VNN1 (0.36) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL8372902 | 0.75 | KMT2A (0.34) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL12395712 | 0.73 | GAA (0.32) | GAAMAPK1 | |
| SCHEMBL12464442 | 0.73 | OPRM1 (0.31) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |