Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032697 | 0.75 | DHFR (0.31) | DHFR | |
| SCHEMBL12260187 | 0.62 | — | — | |
| SCHEMBL14864338 | 0.60 | — | — | |
| SCHEMBL1106903 | 0.57 | — | — | |
| SCHEMBL13840552 | 0.54 | — | — | |
| SCHEMBL14437021 | 0.48 | — | — | |
| SCHEMBL17679320 | 0.44 | — | — | |
| SCHEMBL27855782 | 0.41 | ALDH1A1 (0.35) | — | |
| SCHEMBL1318483 | 0.40 | ALDH1A1 (0.42) | — | |
| SCHEMBL1091555 | 0.40 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |