⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25470434 | 0.88 | — | — | |
| SCHEMBL20936142 | 0.84 | PIK3CD (0.35) | — | |
| SCHEMBL21895773 | 0.80 | — | — | |
| SCHEMBL508753 | 0.72 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL6923986 | 0.69 | — | — | |
| SCHEMBL14179045 | 0.68 | NPC1 (0.31) | — | |
| SCHEMBL13934262 | 0.67 | — | — | |
| SCHEMBL22193225 | 0.67 | NOS3 (0.31) | — | |
| SCHEMBL12197802 | 0.67 | — | — | |
| SCHEMBL22365098 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |