Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20936142 | 0.86 | PIK3CD (0.35) | SMN1; SMN2CYP2D6CYP2C9CHRM2CHRM4 | |
| SCHEMBL29105088 | 0.82 | SMN1; SMN2 (0.31) | SMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL18073626 | 0.82 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL25470434 | 0.82 | — | — | |
| SCHEMBL1698550 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2D6CYP2C9CHRM2CHRM4 | |
| SCHEMBL13491438 | 0.76 | LMNA (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL718764 | 0.72 | PIK3CD (0.41) | SMN1; SMN2CYP2D6CYP2C9CHRM2CHRM4 | |
| SCHEMBL21278138 | 0.72 | PIK3CD (0.41) | SMN1; SMN2CYP2D6CYP2C9CHRM2CHRM4 | |
| SCHEMBL29348305 | 0.72 | — | — | |
| SCHEMBL6050180 | 0.72 | CHRM2 (0.37) | SMN1; SMN2CYP2D6CYP2C9CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| WO-2026099827-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | ALCON INC. (CH) | 2026-05-15 | — | — | WO | claimed |
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| EP-4713721-A1 | UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-03-10 | — | — | US | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-3759528-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | claimed |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-02-02 | — | — | US | claimed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | claimed |
| WO-2012016098-A1 | A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | claimed |
| WO-2011075377-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011071790-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | NOVARTIS AG (CH) | 2011-06-16 | — | — | WO | claimed |
| US-20110140292-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | ALCON INC. (CH) | 2011-06-16 | — | — | US | claimed |
| US-20110133350-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | ALCON INC. (CH) | 2011-06-09 | — | — | US | claimed |
| US-20110102736-A1 | SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | ALCON INC. (CH) | 2011-05-05 | — | — | US | claimed |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | RAD51, ERCC1, LANCL2 | SMN1; SMN2 2894/4885CYP2D6 1379/4885CYP2C9 1263/4885 |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ATRIP, ATR, MACF1 | SMN1; SMN2 4503/4885CYP2D6 4271/4885CYP2C9 4526/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | SMN1; SMN2 4624/4885CYP2D6 2574/4885CYP2C9 1732/4885 |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | CRYAB, CRYZ, CRYAA | SMN1; SMN2 4766/4885CYP2D6 4033/4885CYP2C9 2493/4885 |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | PIGS, ELOVL1, HACD2 | SMN1; SMN2 3064/4885CYP2D6 4158/4885CYP2C9 4326/4885 |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | STRA6, CRYZ, SMCHD1 | SMN1; SMN2 2855/4885CYP2D6 3104/4885CYP2C9 1555/4885 |
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | SMN1; SMN2 4315/4885CYP2D6 3633/4885CYP2C9 1324/4885 |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | CRYZ, CRYAB, CRYAA | SMN1; SMN2 4239/4885CYP2D6 2816/4885CYP2C9 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.