Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348332 | 0.81 | HTT (0.37) | APPLMNAKMT2AMAPK1AAK1 | |
| SCHEMBL14721160 | 0.80 | ESR1 (0.42) | APPLMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL5215418 | 0.80 | ESR1 (0.42) | APPLMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL25972307 | 0.76 | APP (0.45) | APPLMNAKMT2ATRPV1AAK1 | |
| SCHEMBL7746373 | 0.76 | GABRA1 (0.47) | APPLMNAKMT2AFAAHCA1 | |
| SCHEMBL16782681 | 0.75 | MEN1 (0.46) | LMNAKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL16782680 | 0.75 | MEN1 (0.46) | LMNAKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL16811751 | 0.74 | ITGA4 (0.47) | LMNAKMT2AL3MBTL1CA1CA2 | |
| SCHEMBL16410353 | 0.74 | APP (0.37) | APPLMNAKMT2ACYP1A2AAK1 | |
| SCHEMBL16811758 | 0.73 | PARP1 (0.44) | CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |